[BACK] Polio
– A Devastating Disease
During the first half of the 20th century, no illness inspired more dread
and outright panic than polio. Sometimes called infantile paralysis, polio
epidemics struck the US every summer and fall. In 1952, when polio was
at its peak, over 21,000 cases of paralytic polio were reported.1
Click on the question below to learn more about polio
What is polio?
Polio is caused by a virus and is highly contagious … [MORE]
What are the signs and symptoms of polio?
Despite polio’s ability to cause paralysis and death, most people
don’t get sick … [MORE]
What are potential complications of polio?
Polio can affect the muscles, lungs, kidneys, and heart … [MORE]
Who gets polio?
People who haven’t been vaccinated are at greatest risk for getting
polio… [MORE]
How is polio treated?
People with polio were often encased in iron lungs for months or years
… [MORE]
How do you prevent polio?
Vaccination is the only way to prevent polio … [MORE]
Source: 1. Centers for Disease
Control and Prevention (CDC). Epidemiology and Prevention of Vaccine-Preventable
Diseases: The Pink Book. 9th ed. Washington, DC: Public Health Foundation; 2006:97-110.
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What is polio?
- Polio is a highly contagious disease that is caused by a virus that
primarily lives in the intestines and human feces1,2
- The poliovirus is spread from person-to- person primarily through
oral contact with the feces of an infected person (for example, by changing
diapers); it can also spread through contaminated food or water, especially
in areas with poor sanitation systems.1,2 There have also been cases
that have been transmitted by direct oral contact or by droplet spread3
- Once inside the body, the poliovirus multiplies in the throat and
intestinal tract, then travels through the bloodstream where it infects
the brain and spinal cord1,2
- Paralysis occurs because the poliovirus attacks the nervous system
and damages or destroys the nerves that send messages between the brain
and the muscles1,2
Sources:
1. Centers for Disease Control and Prevention (CDC). Epidemiology
and Prevention of Vaccine-Preventable Diseases: The Pink Book.
9th ed. Washington, DC: Public Health Foundation; 2006:97-110.
2. MayoClinic.com. Polio. Available at: http://www.mayoclinic.com/invoke.cfm?id=DS00572
Accessed March 21, 2005. 3. Plotkin SA, Orenstein WA,
eds. Vaccines. 4th edition: WB Saunders. Philadelphia, Pa:
2004;658.
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What are the signs and symptoms of
polio?
Although polio has the ability to cause paralysis and death, most people
who are infected with the poliovirus don’t get sick, but these people
can still spread the virus to others.1,2 Of those who do contract
polio, a small subset will develop either nonparalytic or paralytic polio.
Nonparalytic polio—A small number of infected people develop
this type of polio
- This form of the disease doesn’t lead to paralysis; symptoms
can include: sore throat, fever, nausea, vomiting, constipation, or
diarrhea; most people recover within a week1,2
- Nonparalytic aseptic meningitis (an infection of the outer covering
of the brain) is another type of nonparalytic polio that causes stiffness
of the neck, back, and/or legs in addition to the flu-like symptoms
mentioned above; these symptoms generally last from 2 to 10 days, followed
by a complete recovery1,2
Paralytic polio—Less than 1% of infected people develop
paralytic polio
- This is the most serious form of the disease; it can be fatal without
respiratory support1,2
- Paralytic polio often begins with a fever; other symptoms, including
headache, neck and back stiffness, and constipation, generally appear
a few days later1,2
- Acute flaccid paralysis, which causes the limbs to appear loose and
floppy, often comes on suddenly and usually affects only one side; if
both sides are affected, typically one side is worse than the other1
Learn more about paralytic polio NOW
Post-polio syndrome
- 30 or 40 years after recovery, 25% to 40% of adults who had polio
as children experience muscle weakness and pain in the limbs that were
previously affected by polio, or they develop new weakness or paralysis1,2
- Other signs and symptoms may include fatigue and exhaustion with minimal
activity, breathing or swallowing problems, sleep-related breathing
disorders (for example, sleep apnea), and/or decreased tolerance of
cold temperatures1,2
Sources:
1. Centers for Disease Control and Prevention (CDC).
Epidemiology and Prevention of Vaccine-Preventable Diseases: The
Pink Book. 9th ed. Washington, DC: Public Health Foundation; 2006:97-110.
2. MayoClinic.com. Polio. Available at: http://www.mayoclinic.com/invoke.cfm?id=DS00572.
Accessed March 21, 2005.
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What are potential complications
of polio?
Polio can lead to muscle paralysis that results in deformities of the
hips, ankles, and feet. Although many of the deformities can be corrected
with surgery and physical therapy, these treatments often aren’t
available options in the developing countries where polio still exists.
Other complications associated with the prolonged hospital stay as a result of the paralysis caused by polio infection involve the lungs, kidneys, and heart:
- Pulmonary edema—A potentially life-threatening
condition that fills the lungs with fluid and prevents them from absorbing
oxygen1
- Aspiration pneumonia—An inflammation of the
lungs that is caused by inhaling stomach contents into the lungs1
- Urinary tract infections—Bacterial infections
that can permanently damage the kidneys if not treated promptly1
- Kidney stones—Usually form when urine becomes
too concentrated; they may cause ongoing urinary tract infections or
kidney damage1
- Intestinal obstruction—A partial or complete
blockage of the bowel that prevents
food from moving through the intestinal tract; severe obstructions can
lead to potentially life-threatening complications1
- Myocarditis—An inflammation of the thick muscular
layer of the heart that can
lead to chest pain, an abnormal heartbeat, or congestive heart failure;
it can also cause blood clots to form, which greatly increases the risk
of stroke1
- Cor pulmonale—A heart condition that occurs
when the right side of the heart
can’t pump hard enough to compensate for prolonged high blood
pressure in the arteries and veins in the lungs1
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Who gets polio?
Natural, or “wild-type,” polio has not occurred in the US
since 1979, or in the Western Hemisphere since 1991.1,2
However, children and adults who haven’t been vaccinated against
polio could get the disease if they:
- Travel to a country where polio still exists or where outbreaks have
recently occurred1,2
- Come into contact with infected travelers from countries where polio
still occurs1,2
Find out which countries are still at risk from polio NOW
Sources:
1. Centers for Disease Control and Prevention (CDC).
Epidemiology and Prevention of Vaccine-Preventable Diseases: The Pink
Book. 9th ed. Washington, DC: Public Health Foundation; 2006:97-110. 2. MayoClinic.com.
Polio. Available at: http://www.mayoclinic.com/invoke.cmf?objectid=DS00572.
Accessed March 21, 2005.
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How is polio treated?
Past Treatment Options
In 1916, a large polio outbreak in the United Stated spurred researchers
to find treatments for the disease. What resulted was one of the most
recognized symbols of polio’s long and difficult history.1
The iron lung—About the size and weight of a small
car, the iron lung was a sealed chamber with an electrically driven bellows
that regulated breathing. People with polio were encased in the metal
chambers for months, years, and sometimes for life.1
A number of other therapies, including rigid braces
and body casts, were also tried
in an effort to prevent deformities. However, these treatments often did
more harm than good.1
Then in the 1940s, an Australian army nurse—Sister Elizabeth Kenny—began
treating afflicted limbs with massage, exercise, and warm, moist heat.
While Kenny’s therapy could improve mobility, it could not reverse
permanent paralysis.1
Learn more about the history of polio NOW
Current Treatment Options
Because no cure for polio exists, the focus is on increasing comfort,
speeding recovery, and preventing complications. Today, supportive treatments
for polio include:1
- Antibiotics for secondary infection
- Analgesics for pain
- Portable ventilators for breathing
- Moderate exercise
- A nutritious diet
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Click image to view
childhood immunization schedule.2
How do you prevent polio?
Vaccination is the best way to prevent polio.1
Children
Today, most children in the US receive 4 doses (injections) of inactivated
polio vaccine (IPV) according to the following schedule:1,2
- 2 months old
- 4 months old
- Between 6 and 18 months
- A booster between 4 and 6 years
IPV is 90% effective after 2 doses and 99% effective after 3 doses. Because
the vaccine contains inactivated (killed) poliovirus, it cannot cause polio.
The most common side effects are pain, swelling, or redness at the injection
site; fever, loss of appetite, fussiness and drowsiness.1,3 Learn more about polio vaccines NOW
Adults
Most adults do not need the polio vaccine because they were vaccinated
as children. But there are 3 groups of adults who should consider vaccination
because they are at higher risk than the general adult population.1
- People who are traveling to areas of the world where polio still commonly
occurs
- Laboratory workers who might handle poliovirus
- Health-care workers treating patients who may have polio
Sources:
1. Centers for Disease Control and Prevention (CDC).
Epidemiology and Prevention of Vaccine-Preventable Diseases: The Pink
Book. 9th ed. Washington, DC: Public Health Foundation; 2006:97-110. 2. CDC. Recommended
childhood and adolescent immunization schedule-United States, 2005. MMWR. 2005;53:Q1-Q3. 3. IPOL� (Poliovirus Vaccine Inactivated) Prescribing Information, December 2005.
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Indication
IPOL vaccine is given to infants (as young as 6 weeks of age), children, and adults to prevent polio caused by poliovirus types 1, 2, and 3.
Safety Information
Side effects to IPOL vaccine include injection site pain, swelling, and redness; fever, loss of appetite, fussiness, and drowsiness. Other side effects may occur. If you notice any other problems or symptoms following vaccination, please contact your health-care professional immediately. Vaccination with IPOL vaccine may not protect all individuals.
For more information about IPOL vaccine, talk to your health-care professional.
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